Welcome to the THI Working Paper Series! It is a significant addition to the communication channels of the Triple Helix researchers. The Working Paper Series will be published frequently to share latest research ideas on entrepreneurial university and the triple helix study with our partners and colleges worldwide. We would like to share with you some of our thoughts and impressions, especially from Stanford and Silicon Valley, all showing impressive Triple Helix dynamics and the innovation/ entrepreneurship eco-system. The growing importance of the university, industry and government interaction as an engine of innovation, and the superfluous innovation deficit that arises when one sphere is underperforming or lacking.